| フリガナ | ﾑｶｲ ｻﾄﾙ |
| 英文表記 | MUKAI Satoru |
| 所 属 | 医療学部 健康栄養学科 |
| 職 位 | 准教授 |
| 学 位 | 博士（理学・九州大学） |
| 最終学歴 | 鹿児島大学大学院 農学研究科 生物資源化学専攻 修士課程 |
| 専門分野 | 生化学 細胞生物学 |
| 主な研究テーマ | 食品由来成分、生理活性物質の有用性、機能性の細胞生物学的解析 |
| 担当科目 | 生化学 食品学 栄養学 |
| 学会活動 | 日本生化学会
日本分子生物学会 |
| 主要業績 | （学術論文）
1. Inhibition of non-canonical NF-kB signaling suppresses periodontal inflammation and bone loss.(2023)
Frontiers in Immunology,
Tsukasa Aoki , Fumitaka Hiura , Aonan Li , Nan Yang ,Nana Takakura-Hino, Satoru Mukai, Miho Matsuda, Fusanori Nishimura and Eijiro Jimi
2. RANKL elevation activates the NIK/NF-κB pathway, inducing obesity in ovariectomized mice.(2022)
Journal of Endocrinology, vol.254:1, p27–36
Kayo Mori, Akiko Mizokami, Tomomi Sano, Satoru Mukai, Fumitaka Hiura, Yasunori Ayukawa, Kiyoshi Koyano, Takashi Kanematsu and Eijiro Jimi
3. Adipocyte-specific GPRC6A ablation promotes diet-induced obesity by inhibiting lipolysis.(2021)
The Journal of Biological Chemistry, vol. 296, p100274~100287
#Mukai S, #Mizokami A., Otani T., Sano T., Matsuda M., Chishaki S., Gao J., Kawakubo-Yasukochi T., Tang R., Kanematsu T., Takeuchi H., Jimi E., and Hirata M.(# equal contribution)
4. GLP-1 signaling is required for improvement of glucose tolerance by osteocalcin. (2020)
Journal of Endocrinology vol.244, p285-296
Mizokami A., Mukai S., Gao J., Yasukochi K. T., Otani T., Takeuchi H, Jimi E., and Hirata M.
5. The cytosolic peroxisome-targeting signal (PTS)-receptors, Pex7p and Pex5pL, are sufficient to transport PTS2 proteins to peroxisomes. (2019)
Biochimica et Biophysica Acta, Mol. Cell Res., 1866, p441-449
Mukai S., Matsuzaki T., and Fujiki Y.
6. A newly isolated Pex7p-binding, atypical PTS2 protein P7BP2 is a novel dynein-type AAA-protein. (2018)
The Journal of Biochemistry, vol. 164, p437–447
Niwa H., Miyaychi N. Y., Okumoto K., Mukai S., Noi K., Ogura T. and Fujiki Y.
7. The VDAC2-BAK axis regulates peroxisomal membrane permeability. (2017)
Journal of Cell Biology, 216(3) p709-722
# Hosoi K., # Miyata N., # Mukai S., Furuki S., Okumoto K., Cheng H. E., and Fujiki Y. (# equal contribution)
8. Cul4A-DDB1-Rbx1 E3 ligase controls the quality of the PTS2 receptor, Pex7p. (2014
Biochemical Journal, 463, p65–74
Nanri M. Y., Mukai S., Kuroda K., and Fujiki Y.
9. AWP1/ZFAND6 functions in Pex5 export by interacting with Cys-monoubiquitinated Pex5 and Pex6 AAA ATPase. (2012)
Traffic, vol.13, p168-183
Miyata N., Okumoto K., Mukai S., Noguchi M. and Fujiki Y.
10. Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling. (2011)
Traffic, vol.12, p1067-1083
Okumoto K., Misono S., Non Miyata, Matsumoto Y., Mukai S, and Fujiki Y.
11. In vitro import of peroxisome targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes. (2009)
Biochimica et Biophysica Acta, Mol. Cell Res. 1793, p860-870
Miyata N., Hosoi K., Mukai S., and Fujiki Y.
12. Molecular mechanisms of import of peroxisome-targeting signal type 2 (PTS2) proteins by PTS2 receptor Pex7p and PTS1 receptor Pex5pL. (2006)
Journal of Biological Chemistry, vol. 281, p37311-37320
Mukai S., and Fujiki Y.
13. Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor,
Pex7p, in mammalian cells. (2002)
Journal of Biological Chemistry, vol. 277, p9548-9561
Mukai S, Ghaedi K, and Fujiki Y.
（その他）
＜Review・総説 ＞
1. BAK regulates catalase release from peroxisomes. (2017)
Molecular and Cellular Oncology on line, vol.4, issue 3, article e1306610
Fujiki Y., Miyata N., Mukai S., Okumoto K. and Cheng H. E.
2. Peroxisome biogenesis in mammalian cells. (2014)
Frontiers in Physiology, vol. 5, article 307
Fujiki Y., Okumoto K., Mukai S, Honsho M. and Tamura S.
3. ペルオキシソーム移行シグナル2 型(PTS2)タンパク質輸送とその制御機構 (2012)
金原一郎記念医学医療振興財団 <生体の科学> 第63巻5号
藤木幸夫 向井悟 宮田暖 宮内康弘
4. ペルオキシソーム形成の分子基盤 (2003)
羊土社 実験医学 増刊号
藤木幸夫 向井悟 本庄正則
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